Equilibar Single Use | Precision Fluid Control

Equilibar Single Use Products

Single Use Technology for BioPharmaceutical Processing

Equilibar offers a line of products designed to accommodate the rapidly expanding single use technology (SUT) field in the biopharmaceutical industry. Single use systems (SUS) require lower cost components that can be sterilized through irradiation and disposed of after their useful life.

The Equilibar® dome loaded multi-orifice valve technology is now available in a single use format. The patent pending Equilibar® SD series back pressure regulators and flow control valves are manufactured using USP Class VI polymers and stainless steel. The disposable valve body made of polymer is inserted into a stainless steel support housing with wing nut closure for quick and easy assembly. The Equilibar single use valve for bioprocessing systems is a revolutionary design in single use pressure control.

How it Works

The SD regulator features Equilibar’s patented dome-loaded multiple orifice technology delivering instantaneous control, frictionless operation and superior precision across exceptionally wide flow rate ranges. The stainless steel housing is designed as a permanent part of the process and connects to a dome pilot pressure supply. The disposable body is sold in a pre-sterilized state and comes ready for sterilization up to 50 kGy.

how Equilibar works sanitary

Once assembled, simply apply a pressure to the pilot port in the dome of the Equilibar valve equal to the desired setpoint and the valve does the rest. This pilot pressure forces the upper flexible diaphragm down onto a field of orifices. A rise in inlet pressure lifts the diaphragm up to allow excess pressure to be relieved through the outlet orifices. Similarly, a loss of pressure at the inlet causes the diaphragm to be pushed closer to the orifices, restricting flow and rebuilding pressure at the inlet.

Its strengths are particularly well suited to control the transmembrane pressure in tangential flow filtration or cross-flow filtration, and dP control in virus filtration systems.

The video demonstrates the stability and precision control of the Equilibar single use back pressure regulator

In addition to pressure control applications, the Equilibar SD can be used in on/off and flow control applications in single use processes. Potential advantages for on/off applications include the simple construction, ease of computer automation and low pressure drop.

SDO6 image Single Use valve for biopharma

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Single Use Applications Brochure

Key Performance Advantages

  • Ready for sterilization up to 50 kGy*
  • Simple compact design
  • Wing screw closure for easy assembly
  • Stable across wide flow range
  • Smooth computer operation
  • Versatile – pressure or flow control

*SDO not sold as a sterile device.

exploded view of SDO6 single use back pressure regulator

SDO2 single use valve

Equilibar SDO2 1/4″ single use valve

SDO3 single use valve

Equilibar SDO3 3/8″ single use valve

Equilibar SDO4 single use valve for 1/2"

Equilibar SDO4 1/2″ single use valve

SD Series Specifications

graph of flow curve for SDO6

Download a brochure or contact an Equilibar applications engineer for more information

Download Brochure

SDO dimension image

Equilibar SDO6 single use valve

Equilibar SDO6 3/4″ single use valve

Equilibar SDO8 single use valve

Equilibar SDO8 1″ single use valve




Equilibar News
cover of PI magazine

Process Instrumentation cover story: Ryan Heffner discusses pharmaceutical fluid control

The November issue of Process Instrumentation magazine features a cover article by Ryan Heffner, single use technology manager for Equilibar, that provides a comprehensive overview of fluid control options for the fast-changing pharmaceutical industry. Researchers responding to the COVID epidemic dramatically accelerated the rate of change in the pharmaceutical industry as they developed vaccines and Read More

Read More