Equilibar offers back pressure regulators in our Research Series with extremely low dead volume for use in analytical applications such as High Performance Liquid Chromatography (HPLC). These regulators utilize the 1/16″ HPLC industry standard tube fittings also known Valco-style fittings.
The EB1LF1 with 1/8″ NPT pipe fittings has approximately 3 ml of dead volume during normal operation. However, with optional 1/16″ HPLC (Valco-style) fittings, this unit has only 0.2 ml dead volume.
The EB1LF1 regulator is available in pressures up to 1000 psig with liquid flow rates down to approximately 1 milliliter per hour.
The higher pressure EB1HP1 is also available with Valco-style HPLC fittings with the same low dead volume, with pressures up to 5000 psig. Contact our engineers for a quotation on an Instrument Series regulator with HPLC fittings.
Application in high pressure HPLC Systems
The schematic below shows how the Equilibar precision back pressure regulator can be used to maintain high back pressure on an HPLC column. High pressures are typically required for systems such as Supercritical Fluid Chromatography, where CO2 solvent must be maintained in the range of 2500 to 5000 psig.
Learn more about Equilibar’s Instrument Series Regulators
See the Instrument Series Brochure for additional information about the Instrument Series.
Contact our engineers to discuss your low-dead volume application.