Single Use Control Valve for Biopharmaceutical Applications -

Single Use Control Valve for Biopharmaceutical Applications

Flow control and pressure control for single use BioPharma processes

  • image of the Equilibar single use back pressure regulator for biopharma use
The Equilibar back pressure control valve is now available in a Single Use Design (SD Series) to accommodate the rapidly expanding requirements of BioPharma industry. Single use processes require lower cost components that can be sterilized through irradiation and disposed of after use. The patent pending Equilibar SD series is manufactured using USP Class VI polymers that can be sterilized as an assembly. Only the wetted components and diaphragm are disposable, and are inserted into a permanent stainless steel support housing for quick and easy assembly.

The Single Use Equilibar features the same dome-loaded multiple orifice technology as all Equilibar patented products, delivering instantaneous control, frictionless operation, superior precision, and exceptionally wide flow rate ranges. Its strengths are particularly well suited to control the transmembrane pressure in tangential flow filtration control applications.

The Equilibar SD series valves are manufactured and assembled in a class 7 clean room. Each unit is shipped in two hermetically sealed plastic bags. While typically provided unsterilized so that it can be cleaned as part of a larger assembly, the SD series is optionally available sterilized by Gamma radiation.


schematic showing single use control valve with permanent stainless housing and sterile, USP Class VI wetted components

Pressure range: 0-4 bar(g) / 0 – 60 psig

Tubing size: 1/2″ (12.5 mm) to 1″ (25 mm) tubing

Manufactured using USP Class VI body materials such as:

  • Polycarbonate (such as Ensinger TECANAT™ PC)
  • Copolyester (such as Eastman Tritan MX710)
  • Polypropylene (such as Flint Hill 11R12A)
  • PEEK (such as Röchling SustaPEEK MG)

USP Class VI Diaphragm Materials:

  • Thermoplastic Polyurethane – TPU – (such as Parker ALC Medical Grade)
  • Polyolefin
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Equilibar regulators feature ultra sensitive diaphragm-operated back pressure technology capable of controlling pressure with high precision over a wide range of flows. It fully opens in less than 1% overpressure in most applications. The stability of the Equilibar regulator is unmatched in the industry. The graph below shows the performance of a 1/2” single use regulator with water.

graph of performmance of SD Single Use Valve for biopharmaceutical use

Contact an Equilibar engineer to discuss your single use process control application today.

image of the Equilibar single use back pressure regulator for biopharma use

Equilibar single use back pressure control valve designed for BioPharma industry use

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image of polycarbonate SD single use back pressure valve with stainless steel cap

1/2″ SD Series model with flow-through inlet and perpendicular outlet option

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Equilibar News

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New Year, New Videos

Happy New Year!  If you haven’t checked out the Equilibar YouTube Channel in a while, you may want to do so.  We have created  several new and informative videos in the last few months. In the first video, Equilibar Vice President David Reed gives a laboratory demonstration of a back pressure regulator that has high Read More

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